| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 10 | C$9.10 | - | C$91.00 | |
| 20 | C$6.86 | C$44.80 | C$137.20 | |
| 30 | C$5.27 | C$114.80 | C$158.20 | |
| 60 | C$3.03 | C$364.00 | C$182.00 | |
| 90 | C$2.27 | C$614.60 | C$204.40 | |
| 120 | C$1.89 | C$865.20 | C$226.80 | |
| 180 | C$1.70 | C$1,332.80 | C$305.20 | |
| 270 | C$1.51 | C$2,048.20 | C$408.80 | |
| 360 | C$1.32 | C$2,800.00 | C$476.00 |
Your order is carefully packed and ships within 24 hours. Here's the typical package.
Sized like a regular personal letter (24x11x0.7 cm), with no indication of its contents.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over C$420.00 | Estimated delivery to Canada: 4-7 days |
| Standard Free for orders over C$280.00 | Estimated delivery to Canada: 14-21 days |
| Country | Brand Names |
|---|---|
 Canada | PMS-bupropion SR Taro-bupropion XL Wellbutrin SR Wellbutrin XL |
Zyban is one of the few quit-smoking medicines that works without delivering nicotine, which is why it often comes up in Canadian smoking-cessation conversations alongside patches, gum, and varenicline. We have served customers since 2004, and we offer the 150 mg tablet in a range of pack quantities.
Many Canadians first hear about this medicine at a pharmacy counter or through a provincial smoking-cessation program, often described as a tablet that does not contain nicotine. That framing matters locally because many people trying to stop smoking have already used patches or lozenges and are looking for an option with a different mechanism.
Geography also shapes access. In Toronto, Montreal, Calgary, or Vancouver, a person may have several nearby pharmacies. In a northern Ontario township, a fly-in community in Nunavut, or a small community on the Gaspé Peninsula, the nearest pharmacy may be a long drive or scheduled flight away. Mail-based access can therefore be useful for Canadians who need to maintain a daily course over several weeks.
Zyban is designed to be used as part of a structured quit attempt rather than as an occasional aid on difficult days. The standard adult pattern is 150 mg once daily for the first three days, then 150 mg twice daily with a minimum of 8 hours between doses, giving a usual maximum of 300 mg per day. Treatment normally begins one to two weeks before the chosen quit date so the medicine is already active when smoking stops. Courses commonly run for 7 to 12 weeks, and any longer treatment should be directed by a prescriber.
Its effect is assessed over weeks rather than days. Cravings may ease gradually, and some people find that cigarettes become less rewarding during the early part of the course.
Because the usual regimen is twice daily, timing deserves more thought than with a single morning tablet. Trouble sleeping is a common effect, and the risk can increase when the second dose is taken late in the evening. A workable rhythm for a standard daytime schedule may be a first dose with breakfast around 07:00 and a second in the late afternoon, around 15:00 to 16:00, preserving the minimum 8-hour interval while keeping the second dose away from bedtime.
Shift work is common in Canada, from hospital rotations to mining and oil-sands camps. The same principle applies with the schedule adjusted: anchor the first dose to waking, take the second at least 8 hours later, and avoid taking it close to sleep. Anyone whose schedule changes frequently should confirm a practical dosing plan with a prescriber or pharmacist.
The tablets can be taken with or without food, so meals are a convenient routine anchor rather than a medical requirement. Taking a dose with food may help if nausea occurs, and many people find it easier to remember a medicine when it is tied to a meal they rarely skip.
In practice, that might mean a morning coffee-and-toast routine, a bowl of oatmeal before a winter commute, or a Tim Hortons stop on the way to work. Caffeine does not block the medicine, but anyone experiencing restlessness or poor sleep may want to reduce large or frequent caffeinated drinks. After smoking stops, caffeine can remain in the body longer, so the same number of cups may feel stronger.
Alcohol deserves separate attention. Alcohol tolerance may change during treatment, heavy drinking can increase seizure risk, and abruptly stopping heavy alcohol use while taking bupropion is unsafe. Moderation or avoidance is the prudent approach, and anyone who drinks heavily should seek medical advice before changing their alcohol use.
A key serious risk is a dose-related lowering of the seizure threshold. The medicine is not suitable for people with a seizure disorder, a current or previous diagnosis of bulimia or anorexia nervosa, or those abruptly withdrawing from alcohol or sedatives. It must not be used with a monoamine oxidase inhibitor or within 14 days of stopping one. Canadian labelling also identifies diabetes treated with insulin or oral glucose-lowering medicines as a factor that may increase seizure risk, partly because low blood sugar can lower the seizure threshold.
The medicine may affect judgement, thinking, or motor skills, so avoid driving or operating machinery until its effects are clear. In much of Canada, this is not a minor caution: a long winter drive or a remote work road is a poor place to discover light-headedness or unusual jitteriness.
Frequently reported effects include insomnia, dry mouth, headache, nausea, dizziness, constipation, and a changed sense of taste.
General patient sentiment in Canadian cessation groups, mood-disorder communities, and pharmacy follow-up conversations tends to cluster around a few themes. Some people value that no nicotine is involved, especially if they disliked chewing nicotine gum or found patches irritating under winter clothing. Others focus on whether cigarettes gradually feel less rewarding.
A clearly illustrative comment of the kind found in smoking-cessation discussions might read:
"During the first week, I mainly noticed a dry mouth. By the middle of the second week, the after-supper cigarette felt less compelling. Sleep was difficult, so I discussed moving my second tablet to the middle of the afternoon."
This example is not a verified individual case, and responses vary widely. It reflects two practical themes that recur in patient discussions: dose timing and hydration.
The difficulties people describe are fairly predictable, and some can be managed when anticipated.
Canadians encounter smoking-cessation medicines through several channels, and the experience differs between them.
Prescription-drug prices in Canada are not standardized. The amount paid for the same medicine can differ between pharmacies, and dispensing fees vary by province, territory, and store. Customers comparing local options should ask each pharmacy about its current price and service fees.
Online medicine access has become a familiar part of Canadian health care, and the reasons are mostly practical. Pharmacies and online pharmacy operations are licensed by provincial or territorial regulators, with national coordination through the National Association of Pharmacy Regulatory Authorities (NAPRA), so applicable rules depend partly on where a customer lives.
Distance is one factor. For households several hours from the nearest pharmacy, or in communities where winter road conditions affect travel, delivery can remove a practical barrier. Privacy is another factor: some people prefer not to discuss smoking cessation across a counter in a small community. Continuity also matters because having enough tablets for the planned course can reduce the need for repeated pharmacy trips.
An online channel cannot provide every element of an in-person consultation. Pharmacy counter service can include a pharmacist reviewing other medicines, checking blood pressure, and identifying interactions. Our team handles product, payment, and delivery questions but does not provide clinical advice. Anyone with a complex medication list or a history of seizures, eating disorders, or mood disorders should consult a Canadian prescriber or pharmacist.
Canada does not operate one identical national drug plan. Coverage flows through provincial and territorial programs such as the Ontario Drug Benefit, Quebec's RAMQ public prescription drug insurance plan, and BC PharmaCare, alongside federal routes including Non-Insured Health Benefits for eligible First Nations and Inuit clients, employer benefits, and private insurance.
Whether a smoking-cessation medicine is listed by a particular plan, what clinical criteria apply, how long support lasts, and what the patient pays are plan-specific questions that may change. No coverage, eligibility, reimbursement, or co-payment should be assumed. A public or private plan may reduce out-of-pocket cost but can impose plan rules or documentation requirements. Paying privately may avoid coverage criteria, but it does not remove the prescription requirement that applies at Canadian pharmacies.
The active ingredient is bupropion, an aminoketone antidepressant that acts mainly by reducing the reuptake of dopamine and norepinephrine in the brain rather than serotonin. Nicotine drives dopamine release in reward pathways; when a person stops smoking, that signalling falls, contributing to low mood, poor concentration, irritability, and cravings. Bupropion supports these pathways through a different mechanism, which can reduce withdrawal symptoms and make smoking feel less rewarding.
A rough analogy is that nicotine has repeatedly stimulated the brain's reward system for years. When smoking stops, that stimulation disappears. Bupropion does not supply nicotine, but it can help support the affected signalling pathways while the brain adjusts.
Because the active ingredient is the same, Zyban must not be combined with other bupropion-containing products, including Wellbutrin or Wellbutrin SR. Combining them can raise the total dose and increase seizure risk.
Zyban is authorized in Canada as an aid to smoking cessation. Bupropion is also used under antidepressant brands for major depressive disorder in adults, but those products have a different therapeutic purpose. Canadian smoking-cessation practice generally combines medication with counselling or behavioural support when possible.
A person seeking treatment primarily for depression should be assessed for an appropriately indicated antidepressant product. Zyban should not be treated as a substitute for a depression assessment or combined with another bupropion product.
Interaction risk deserves careful review because bupropion inhibits the CYP2D6 enzyme and is itself metabolized mainly through CYP2B6.
No specific food is prohibited. Grapefruit is not a characteristic interaction for bupropion, and ordinary Canadian meals do not require adjustment.
Recent smoking-cessation evidence increasingly emphasizes matching treatment to the individual rather than treating one medicine as universally best. Comparative research has often found higher quit rates with varenicline, while bupropion and nicotine-replacement therapy remain established options. Previous experience, health conditions, tolerability, interactions, and cost all influence the choice.
Evidence has also helped clarify neuropsychiatric safety while reinforcing the need to monitor mood and behaviour. Clinicians may consider smoking-cessation medication for people with mental health conditions after an individual assessment. Other areas of continuing research include extended treatment, carefully supervised combinations with nicotine replacement, and support for people trying to stop vaping or other nicotine use.
| Option | Mechanism | Practical considerations |
|---|---|---|
| Zyban (bupropion tablets) | Non-nicotine medicine that supports dopamine and norepinephrine signalling | Twice-daily dosing; unsuitable with a seizure disorder or a history of bulimia or anorexia nervosa; insomnia and dry mouth are common |
| Champix (varenicline) | Partial agonist at nicotine receptors | Often associated with higher quit rates; nausea and vivid dreams are common concerns |
| Nicotex and other nicotine-replacement products | Supply controlled nicotine without tobacco smoke | Available in several forms; correct technique matters; combination with bupropion requires clinical guidance |
| Behavioural support alone | Counselling, quitlines, and group programs | No medicine interactions; outcomes generally improve when behavioural support is combined with medication |
For someone whose main concern is low mood rather than tobacco use, assessment for an antidepressant treatment is the more appropriate route, and that decision belongs with a Canadian prescriber.
Zyban is authorized for sale by Health Canada and has a Drug Identification Number (DIN). Bausch Health Canada Inc. is identified as the manufacturer of the Canadian product. Bupropion appears on Health Canada's Prescription Drug List, so a valid prescription is required at Canadian pharmacies. Our store policy does not require customers to submit a prescription, and we do not issue prescriptions or provide prescribing services. Suspected adverse reactions can be reported to Health Canada through the Canada Vigilance Program, while health-technology assessments relevant to Canadian drug plans are conducted by Canada's Drug Agency.
Pharmacy regulation remains a provincial and territorial responsibility, with coordination through NAPRA. Access rules and dispensing practices can therefore differ between provinces and territories.
Store at 20-25 °C. Protect from light and moisture. Canadian seasonal conditions make careful handling especially important.
Canadian destinations range from major urban centres to rural and northern communities, so delivery planning matters. Express delivery is tracked and estimated at 4 to 7 days. Standard delivery is estimated at 14 to 21 days and does not include tracking. Visa, Mastercard, American Express, Bitcoin, and USDT are accepted at checkout. Express shipping is free over CAD 300, and Standard shipping is free over CAD 200.
The table below presents representative estimates for selected Canadian cities using the configured delivery ranges.
| City | Express | Standard |
|---|---|---|
| Edmonton | ≈ 4 days | ≈ 18 days |
| Winnipeg | ≈ 6 days | ≈ 16 days |
| Kitchener | ≈ 5 days | ≈ 17 days |
| St. Johns | ≈ 7 days | ≈ 18 days |
| Sherbrooke | ≈ 7 days | ≈ 15 days |
Remote, northern, and island destinations may fall at the longer end of each estimated range, particularly during winter disruptions. Our email and online chat team can assist with delivery questions.
Zyban provides a non-nicotine option for the difficult weeks of stopping smoking. The usual adult regimen uses 150 mg tablets, begins one to two weeks before the quit date, and commonly continues for 7 to 12 weeks. The medicine can reduce withdrawal symptoms and make smoking feel less rewarding, especially when combined with counselling, quitlines, or pharmacist-led support.
Its limitations are equally important: seizure-related contraindications, restrictions involving eating disorders and monoamine oxidase inhibitors, interaction concerns for people taking several medicines, and sleep disruption when doses are taken too late. Canadians comparing local pharmacy access with delivery should also consider the value of an in-person medication review. We offer pack quantities from 10 to 360 tablets, two delivery options with clearly stated estimates, and support by email and online chat.
My prescription says Wellbutrin, but I was looking at Zyban. Can I swap the brand myself?
Yes, if your prescription is for bupropion 150 mg and it does not require a specific brand, Zyban can be used as the bupropion 150 mg option. If your prescription names a specific release form or says not to substitute, follow that wording.
I only need a small first Zyban order. Do you have less than 60 tablets?
Yes. For Zyban 150 mg, the available quantities include 10, 20 and 30 tablets, as well as larger options.
I want the expiry date left visible on the Zyban box. Do you remove the medicine packaging?
No. We do not remove Zyban from its medicine packaging. The exact expiry date remains printed on the pack you receive.
| Active ingredient | Bupropion |
|---|---|
| Drug class | Aminoketone antidepressant |
| Dosage form | Tablet |
| Strengths | 150 mg |
| Route | Oral |
| Storage | Store at 20-25 °C. Protect from light and moisture. |
| ATC code | N06AX12 |
This product has 93 ratings, but only 6 written reviews so far. Share your experience and help other customers.
I received my order normally.
The quality was good.
I'll order Zyban again.
I asked about available package quantities, and support gave a concise, useful answer.
I found everything pretty reasonable.
Packed securely and neatly.